My wife and I took a long weekend for our anniversary and stayed in Asheville at the Downtown Inn and Suites. This is a fairly old hotel, the people were friendly and the rooms were clean, but the best part is it is right downtown with free parking. Less than a block away are Thirsty Monk and the Green Man pub. Down the street is Asheville Brewing Co., then French Broad is a short walk from there. I had the oyster stout at the Lobster Trap, brewed on the same kinda sabco system I have.
It's a nice beer town and they seem happy to have everything local for sale. I'd go back.